Product Description
| Description | Anti- Arl3 Mouse Monoclonal Antibody |
| Another Name | Anti- Arl3 Mouse Monoclonal Antibody |
| Catalog Number | NL25070 |
| Size: | 100 µl |
| Tested Applications: | ELISA WB ELISA:1:1000-1:5000 WB:1:500-1:2000 |
| Cited Applications: | ELISA WB |
| Tested Reactivity: | Human , mouse |
| Full Name | ADP-ribosylation factor-like 3 |
| Gene Symbol: | ARFL3 |
| Immunogen : | Synthetic peptide of human ARL3 |
| Concentration: | 1mg/ml |
| Host/Isotype: | Mouse/IgG |
| Class: | Monoclonal |
| Type: | Antibody |
| Predicted mv: | 20KDa |
| Observed mv: | 20KDa |
| Uniprot: | P36405 |
| Constituents: | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Storage Conditions: | Store at -20°C for one year after shipment |
Background: | ADP-ribosylation factor-like 3 is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL3 binds guanine nucleotides but lacks ADP-ribosylation factor activity. Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms |
Tested Applications: WB
